Peptide Database

Peptide NameyusYn signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC141H230N44O41S3

DescriptionStandard

        MHLIRAAGAVCLAVVLIAGCRFNEDQHQAEG
    

Molecular Weight3293.80 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-1.34

Net Charge (pH 7.4) -1.69

Charge Density (pH 7.0) -0.0432

GRAVY Index0.51

Hydrophobic Moment 0.41

Boman Index0.19

Instability Index37.84

Aliphatic Index 110.32

Aromaticity 0.0323

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1358.65

LogP -12.92

H-bond Donors 48.0

H-bond Acceptors 45.0

Rotatable Bonds 109.0

Heavy Atoms 229.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081982 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization alpha-amylase (AmyS) secretion

TargetBacillus subtilis 1A751

Activity234.0 U/mL

MethodAmylase activity assay

RECORD: Rec_0209162 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/