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MYP_058596
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C52H81N23O16
Standard
Sequence
RGVSGHGQHGVHG
Physicochemical Analysis
1284.34 Da
9.77
1.02
0.67
0.0786
-0.92
0.42
-0.02
-21.23
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
623.78
-9.90
22.0
20.0
41.0
91.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0240180 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HSV-1 McIntyre strain
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0251722 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HSV-1
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0272036 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0310771 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Coxsackie virus 971 PT B2
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0347494 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
HHV-1 McIntyre strain | Vero cells
321.1 μg/mL
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperFurther studies on the antiviral activity of alloferon and its analogues. | Kuczer M, Midak-Siewirska A, Zahorska R, Luczak M, Konopińska D. | J Pept Sci. 2011 Nov;17(11):715-9. | DOI:10.1002/psc.1388 | PMID:21766388 PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
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