‹ ›
MYP_058596
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C52H81N23O16
Standard
Sequence
RGVSGHGQHGVHG
Physicochemical Analysis
1284.34 Da
9.77
1.02
0.67
0.0786
-0.92
0.42
-0.02
-21.23
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
623.78
-9.90
22.0
20.0
41.0
91.0
3.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0000475 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 38.5%, C 61.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0021484 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Vero cells
Hemolysis
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0033112 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Vero cells,LLC-MK2 cells and Hep-2 cells up to 143
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0038770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
Coxsackie virus 971 PT (971 PT CVB2) | LLC-MK2 cells
577.7 μg/mL
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperFurther studies on the antiviral activity of alloferon and its analogues. | Kuczer M, Midak-Siewirska A, Zahorska R, Luczak M, Konopińska D. | J Pept Sci. 2011 Nov;17(11):715-9. | DOI:10.1002/psc.1388 | PMID:21766388 PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0045771 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
HHV-1 | Vero cells
277.5 μg/mL
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperFurther studies on the antiviral activity of alloferon and its analogues. | Kuczer M, Midak-Siewirska A, Zahorska R, Luczak M, Konopińska D. | J Pept Sci. 2011 Nov;17(11):715-9. | DOI:10.1002/psc.1388 | PMID:21766388 PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5