Peptide Database

Peptide Nametryptophan-modified human lactoferricin (LFH W8)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC88H134N28O20S2

DescriptionStandard

        TKCFQWQWNMRKVRG
    

Molecular Weight1968.31 Da

Isoelectric Point (pI)11.01

Net Charge (pH 7.0)3.39

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.2258

GRAVY Index-1.25

Hydrophobic Moment 0.36

Boman Index-0.35

Instability Index1.21

Aliphatic Index 19.33

Aromaticity 0.2000

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 827.64

LogP -6.58

H-bond Donors 31.0

H-bond Acceptors 26.0

Rotatable Bonds 65.0

Heavy Atoms 138.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010665 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyLactoferricin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0033336 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLactoferricin

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity74 μM

MethodMIC

RECORD: Rec_0087948 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLactoferricin

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity500 μM

MethodMIC

RECORD: Rec_0148319 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity500 μM

MethodMIC

RECORD: Rec_0403352 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity74 μM

MethodMIC