Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length591 amino acids

Chemical FormulaC2923H4690N800O893S21

DescriptionStandard

        MGHRDPKVILELQRKQLATGIKISASNGKMEKCLDYITQKGAPHALPATDMDALMVELRRQIEQLGVSTVTQQLRDMGVPGSAEARAGTEQVSQLLDPRSQQLQPQTAAQTVELPQAPHTPAGGSIYRPETVKLRSLWKRRLLVLHKKIQISIRFQRREAEGTQRCGSFPCFVLFVTVFTLSRCDDPGLKLRIFQKGLDNANGAVKEFLENKIRDLRVGKLIGYGNGSLQFNISYTKLLNFTIINSSMTIVPDTGIQITISNSNATINSVWKARNETSEVKNITVMKVSEASITMVINISKNDPEYPLFSVVNCTTDIKKIDIKLGNAIEPMFENKEELKNEVLSLLNPQVCRAVTENFELWTTNISTFSGRYDVNRYVGINYQLVNSPVFTEKYFDVNINGSFYAINGTDHPVAPANFSFLDSNDSAMCIGISEAALNSVAQAYYDARFFRLTFTHPMINKSVAEWNGEQNSIYARGILNATKAPEFILNPKNITMNFNADLLLVTKEPNKTRVLVVTINTESSISATVSISEANSTLNVSGSLTLNSLDLNVISNQTTTNTKDEELKKSMKEFLEKPLMEYFNKLYTKD
    

Molecular Weight66000.69 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)5.03

Net Charge (pH 7.4) 4.25

Charge Density (pH 7.0) 0.0085

GRAVY Index-0.25

Hydrophobic Moment 0.75

Boman Index0.00

Instability Index36.89

Aliphatic Index 90.56

Aromaticity 0.0745

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268722 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocaecilia unicolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria