Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length386 amino acids

Chemical FormulaC1932H3059N497O544S18

DescriptionStandard

        DKGEKMLKMWYSLLLCLLFLQLEANPGLKVRITQKGLDYGRKIGMELLKQEVLKETFPGWSGQESFLAMKINYMISKLRIGAVDFPETSASFIPGIGISLSMAHASATISADWRMETWLLKDQGGITVSISGLFIAVIFKVSRDSTGHLSILLHNCQLSVSRVKVKLNGGSSWIASFLSGYLQKPIQNKLDENLCLNIKHRIQMMDAQLRKYNVSSQIDAFAQIDYSLVSSPAVFKSHINLDLKGTVYPVGNHTDPPFVPAPFGLSNHGDSMLYLGVSNYFLKSASLAYYRAGAFNITISKELAATFNLNTTILKGFVPEIALHYVTACPVLLKLMATSPPVVSLQADRCSLQITGCVEVFAVLPNSTSQHIFTGNLVSSMNYKIT
    

Molecular Weight42530.13 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)9.50

Net Charge (pH 7.4) 8.66

Charge Density (pH 7.0) 0.0246

GRAVY Index0.19

Hydrophobic Moment 0.71

Boman Index0.16

Instability Index34.65

Aliphatic Index 103.32

Aromaticity 0.0933

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 47245.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064867 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence