Peptide Database

Peptide NameNeuromedin-U-8

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC50H76N16O11

DescriptionStandard

        QFLFRPRN
    

Molecular Weight1077.24 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.2200

GRAVY Index-1.02

Hydrophobic Moment 0.38

Boman Index-0.39

Instability Index29.40

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 468.21

LogP -3.50

H-bond Donors 16.0

H-bond Acceptors 13.0

Rotatable Bonds 33.0

Heavy Atoms 77.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186626 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyNeuromedin-U

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasoconstrictor Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour