Peptide Database

Peptide NameHBD3 (4-45)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC202H352N72O56S6

DescriptionStandard

        NTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
    

Molecular Weight4877.79 Da

Isoelectric Point (pI)10.08

Net Charge (pH 7.0)10.70

Net Charge (pH 7.4) 10.39

Charge Density (pH 7.0) 0.2547

GRAVY Index-0.95

Hydrophobic Moment 0.60

Boman Index-0.46

Instability Index58.23

Aliphatic Index 53.33

Aromaticity 0.0476

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2162.30

LogP -26.20

H-bond Donors 86.0

H-bond Acceptors 73.0

Rotatable Bonds 172.0

Heavy Atoms 336.0

Ring Count 3.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365993 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetShigella flexneri CICC 21534 LD90

Activity3.3

RECORD: Rec_0424571 VERIFIED: YES