Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC766H1196N200O245S13

DescriptionStandard

        MKSYVDARVKNLTYILFSTGSFEPQKCWKNNIGHCRRRCLDTERCILLCRNKLSCCIYIIISHEYTQRPAFPMIHLEDITFDYSDVDSFTVSMLNDLITFDTTKFGETMTPETNTPETTVPPSETTTPETTMPPSETATSETMPPPSQTALTHN
    

Molecular Weight17543.73 Da

Isoelectric Point (pI)5.14

Net Charge (pH 7.0)-6.19

Net Charge (pH 7.4) -6.75

Charge Density (pH 7.0) -0.0402

GRAVY Index-0.43

Hydrophobic Moment 0.60

Boman Index-0.02

Instability Index60.69

Aliphatic Index 62.66

Aromaticity 0.0844

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7110.54

LogP -78.34

H-bond Donors 252.0

H-bond Acceptors 256.0

Rotatable Bonds 559.0

Heavy Atoms 1224.0

Ring Count 31.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214168 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9593

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence