Peptide Database

Peptide NameInterleukin-33

Function Ontology

Antiviral

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC812H1251N205O264S7

DescriptionStandard

        HDSSITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET
    

Molecular Weight18333.29 Da

Isoelectric Point (pI)4.81

Net Charge (pH 7.0)-13.55

Net Charge (pH 7.4) -14.28

Charge Density (pH 7.0) -0.0836

GRAVY Index-0.46

Hydrophobic Moment 0.49

Boman Index0.00

Instability Index47.32

Aliphatic Index 81.17

Aromaticity 0.0864

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14690.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7534.26

LogP -75.18

H-bond Donors 257.0

H-bond Acceptors 265.0

Rotatable Bonds 615.0

Heavy Atoms 1288.0

Ring Count 29.0

Amide Bonds 173.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0061331 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-1 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-1 family Antiviral Chemokine-like Host defense