Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC934H1407N207O281S9

DescriptionStandard

        IDDLAEVDYSLNTFPAVFRPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSLFAYYTAGAFNITIAEETCSYFNISTEMFGSIIPEVSKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20319.97 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0778

GRAVY Index0.32

Hydrophobic Moment 0.61

Boman Index0.26

Instability Index44.26

Aliphatic Index 92.24

Aromaticity 0.1421

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7701.07

LogP -79.49

H-bond Donors 261.0

H-bond Acceptors 276.0

Rotatable Bonds 642.0

Heavy Atoms 1431.0

Ring Count 38.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113084 VERIFIED: NO

Provenance & Taxonomy

OrganismScopus umbretta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria