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MYP_058468
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Basic Information
Antifungal peptide (Cm-p1; Plants)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C51H89N19O16
Standard
Sequence
SRSELIVHQR
Physicochemical Analysis
1224.37 Da
9.34
0.55
0.29
0.0550
-0.83
0.23
-0.39
82.97
107.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
598.55
-6.88
22.0
18.0
42.0
86.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058769 VERIFIED: YES
Provenance & Taxonomy
Cenchritis muricatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Free (very possibly)
Bio-Activity Profile
Antimicrobial Antifungal
Aspergillus niger
41 μM
MIC
PMID22210491 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22210491/
RECORD: Rec_0078920 VERIFIED: YES
Provenance & Taxonomy
Cenchritis muricatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
32 μg/mL
MIC
PMID25921828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25921828/
RECORD: Rec_0097845 VERIFIED: YES
Provenance & Taxonomy
Cenchritis muricatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Free (very possibly)
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
20 μM
MIC
PMID22210491 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22210491/
RECORD: Rec_0103296 VERIFIED: NO
Provenance & Taxonomy
Cenchritis muricatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Fungicide Anti-Candida Cytotoxic Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID22210491 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22210491/; https://www.uniprot.org/uniprotkb/B3EWI7/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0141160 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Cenchritis muricatus [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
A. niger
41 μM
MIC
PaperFunctional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus.
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