Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC207H331N61O77S5

DescriptionStandard

        MEKVLDLDVQVKENNNSNDSAGDERITSHSLCTPGCAKTGSFNSFCC
    

Molecular Weight5066.53 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.44

Net Charge (pH 7.4) -3.78

Charge Density (pH 7.0) -0.0732

GRAVY Index-0.53

Hydrophobic Moment 0.40

Boman Index-0.09

Instability Index14.99

Aliphatic Index 55.96

Aromaticity 0.0426

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2263.48

LogP -32.90

H-bond Donors 80.0

H-bond Acceptors 80.0

Rotatable Bonds 171.0

Heavy Atoms 350.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310891 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus aureus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence