MYP_058397
Unnamed
Antimicrobial
Antiviral
▸
Antiviral
▸
Antiviral mechanism
▸
Standard
30 amino acids
C148H228N38O43S6
Standard
KIPCGESCVWIPCVTSIFNCKCENKVCYHD
3420.01 Da
6.72
-0.21
-0.56
-0.0069
0.11
0.41
0.10
15.02
68.00
0.1000
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1291.17
-11.63
49.0
50.0
107.0
235.0
7.0
31.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0321804
VERIFIED: YES
Provenance & Taxonomy
Chassalia parviflora [Animal]
Defensin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
4-20, 8-22, 13-27
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0327952
VERIFIED: YES
Provenance & Taxonomy
Chassalia parviflora [Plant]
Defensin
58431
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization (N termini to C termini)
Cyclization (N termini to C termini)
4-20, 8-22, 13-27
Disulfide bonds between Cys4 and Cys20, Cys8 and Cys22,Cys13 and Cys27.
Bio-Activity Profile
Anti-HIV
Entry inhibition
HIV
0.05-0.275 μM
EC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
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