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MYP_058397
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
30 amino acids
C148H228N38O43S6
Standard
Sequence
KIPCGESCVWIPCVTSIFNCKCENKVCYHD
Physicochemical Analysis
3420.01 Da
6.72
-0.21
-0.56
-0.0069
0.11
0.41
0.10
15.02
68.00
0.1000
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1291.17
-11.63
49.0
50.0
107.0
235.0
7.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010505 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0094865 VERIFIED: YES
Provenance & Taxonomy
Chassalia parviflora [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
0.05-0.275 μM
EC50
PMID10691702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10691702/
RECORD: Rec_0117840 VERIFIED: NO
Provenance & Taxonomy
Chassalia parviflora [Plant]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-20; 8-22; 13-27
Bio-Activity Profile
Antimicrobial Antiviral
RECORD: Rec_0187494 VERIFIED: YES
Provenance & Taxonomy
Chassalia parvifolia [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antiviral Anti-HIV
HIV-1
0.050-0.275 μM
EC50
PaperPubMed PMID 10691702 PMID10691702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10691702/
RECORD: Rec_0286676 VERIFIED: YES
Provenance & Taxonomy
Chassalia parviflora [Animal]
Defensin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
4-20, 8-22, 13-27
Bio-Activity Profile
Antimicrobial Antiviral
HIV:inhibition the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells
0.05-0.275 μM
EC50
PaperCyclotides as natural anti-HIV agents PMID18008336 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18008336/
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