Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC468H750N136O149S13

DescriptionStandard

        MKSISVVCAVALTVTCICILQTTAVPFSQSETHPQAEQQQQMDSEVPQSEQQWTAASAAEETLRPEEVLFRTKRQSHLSLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight11082.63 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -0.91

Charge Density (pH 7.0) -0.0042

GRAVY Index-0.21

Hydrophobic Moment 0.57

Boman Index-0.04

Instability Index74.87

Aliphatic Index 64.04

Aromaticity 0.0606

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4626.70

LogP -56.45

H-bond Donors 169.0

H-bond Acceptors 164.0

Rotatable Bonds 367.0

Heavy Atoms 766.0

Ring Count 13.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279044 VERIFIED: NO

Provenance & Taxonomy

OrganismAstyanax mexicanus [Animal]

FamilyHepcidin family

Tax ID7994

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0350934 VERIFIED: NO