Peptide Database

Peptide NamePle-ACD

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC165H230N44O48S7

DescriptionStandard

        GFGCPWDEDDMQCHNHCIKGYKGGYCGGFVCKCY
    

Molecular Weight3822.31 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.53

Charge Density (pH 7.0) -0.0331

GRAVY Index-0.50

Hydrophobic Moment 0.42

Boman Index0.06

Instability Index27.08

Aliphatic Index 20.00

Aromaticity 0.1765

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1462.11

LogP -13.84

H-bond Donors 55.0

H-bond Acceptors 56.0

Rotatable Bonds 120.0

Heavy Atoms 264.0

Ring Count 10.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131631 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct based on Plectasin deletion variant [Synthetic]

FamilyPlectasin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus aureus ATCC 43300. Recombinant production:yeast:Pichia pastoris: X33 strain, pPICZaA plasmid, expressed supernatant was used for activity screen. Activity data provided by Jianhua Wang