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MYP_058307
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Basic Information
ACTH4-10
Antimicrobial
Antiviral
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
7 amino acids
C37H51N9O10S
Standard
Sequence
MEHFPGP
Physicochemical Analysis
813.92 Da
5.22
-1.41
-1.68
-0.2014
-0.80
0.28
0.20
10.50
0.00
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
286.32
-1.22
8.0
11.0
21.0
57.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0139151 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
ACTH4
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for ACTH4-10 (Rattus norvegicus): PMID 16523722 PMID16523722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16523722/
RECORD: Rec_0197616 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Opioid
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID16523722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16523722/
RECORD: Rec_0203983 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0297350 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0347300 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Immunomodulatory
Encephalomyocarditis virus (Hybrid physiological effects); MDCK
40 %
Survival of mice
PaperAntiviral properties of structural fragments of the peptide Selank. | Andreeva LA, Nagaev IY, Mezentseva MV, Shapoval IM, Podchernyaeva RY, Shcherbenko VE, Potapova LA, Russu LI, Ershov FI, Myasoedov NF. | Dokl Biol Sci. 2010 | PMID:20506839 PMID20506839 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20506839/
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