Peptide Database

Peptide Namebeta-Melanocyte-stimulating hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC90H128N26O26S

DescriptionStandard

        DGSYKMNHFRWSGPPKD
    

Molecular Weight2022.20 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0500

GRAVY Index-1.71

Hydrophobic Moment 0.24

Boman Index-0.28

Instability Index67.51

Aliphatic Index 0.00

Aromaticity 0.1765

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.13

LogP -8.61

H-bond Donors 29.0

H-bond Acceptors 29.0

Rotatable Bonds 62.0

Heavy Atoms 143.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060558 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser guldenstadti [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0102065 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyPOMC

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0145859 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyMelanocyte-stimulating hormone

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0165258 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/