Peptide Database

Peptide NameFragment 324-329

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC35H59N7O10

DescriptionStandard

        YLTTLK
    

Molecular Weight737.88 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.1263

GRAVY Index0.17

Hydrophobic Moment 0.37

Boman Index0.13

Instability Index-5.82

Aliphatic Index 130.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 295.53

LogP -1.25

H-bond Donors 11.0

H-bond Acceptors 11.0

Rotatable Bonds 23.0

Heavy Atoms 52.0

Ring Count 1.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014689 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLactoferrin-derived

Tax ID9913;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Replication inhibitor Cytoprotective

TargetSimian rotavirus (Replication); HT-29

Activity1355.207466 μM

MethodEC50

PaperInvolvement of bovine lactoferrin metal saturation, sialic acid and protein fragments in the inhibition of rotavirus infection. | Superti F, Siciliano R, Rega B, Giansanti F, Valenti P, Antonini G. | Biochim Biophys Acta. 2001 | PMID:11687297 PMID11687297 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11687297/

RECORD: Rec_0136392 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0187353 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLactoferrin-derived

Tax ID9913

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral Antibacterial