Peptide Database

Peptide NameColicin pyocin immunity family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length913 amino acids

Chemical FormulaC4399H7072N1280O1322S27

DescriptionStandard

        MRNGNESSSSDSMTVSGSRPSGVHWGGGRGNNGGGDRHSSHKAVNKPKVDLLKTPEMQAYMAVGGMPAVITLIDNVWGITLTRHSVMSFLETNLSRVGAWAMRTSPIGVAVLGMMPSKIALDPPIGHYFTTPALPANRVTDTPKEALQVATDVVVNVRISDVTDAGVQHAVLHKTPVAIQRIPVVKAIATIRPNVFTAAVPGITPMHISVVDTIASENEAKLAAPTGKPTVTPIESTPVREFSLPVGRHTHDAIIVFPDSVDVEPIYLSVIRITSTHEIRQEAYNTYEIAKTEREVAERNRVQKKPFGSFIEEMTLQKTLMDSQVAETAAHIILLESKLTLLRQEEGQAWHQREHLIRIRGNKKFKYLHEVHGLRKLAQAKQGEIDVINQSIAKLKTEEMGLLMQQQRVNADLETAKITEPQRVENAHLTAEAAEKAARDRRISEEIAATEAKRQRMENERLAEQEWQRVEHGRLAAEKAARDRRISEEMAATEAKRQRMENERLAEQERQRVEGPKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVVLSLREAAELHNSFLAAQEQLSAIATTSASGSVAAMIALGIYQTKVGESSERPPGWNVNPKFVGSISLSAMGLPATESLASQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAAQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAESRPILAPPGSTPATLQHTGEMIIKPVITPTILPLPQLYARDFHDYIIWFPADSGLEPVYVYLKSPRDEPGVVTGHGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAAFWREVANDPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVYDVDNLRVATPKRHIEIHSRRGGK
    

Molecular Weight99908.75 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)9.09

Net Charge (pH 7.4) 7.20

Charge Density (pH 7.0) 0.0100

GRAVY Index-0.32

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index45.58

Aliphatic Index 84.12

Aromaticity 0.0537

Extinction Coeff. Reduced 84340.00

Extinction Coeff. Oxidized 84465.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191425 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia pseudotuberculosis [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence