Peptide Database

Peptide NameCathelicidin-1 (5-26), CATH-1 (5-26), Fowlicidin-1 (5-26)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC125H205N33O27

DescriptionStandard

        VWPLVIRTVIAGYNLYRAIKKK
    

Molecular Weight2602.17 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)4.73

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.2150

GRAVY Index0.31

Hydrophobic Moment 0.70

Boman Index0.10

Instability Index-5.86

Aliphatic Index 137.27

Aromaticity 0.1364

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 987.06

LogP -3.25

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 84.0

Heavy Atoms 185.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001487 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetListeria monocytogenes ATCC 19115

Activity2.4 μM

MethodMIC

RECORD: Rec_0135824 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity11 μM

MethodHemolysis

RECORD: Rec_0136675 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity4.8 μM

MethodMIC

RECORD: Rec_0160200 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity0.6 μM

MethodMIC

RECORD: Rec_0363058 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028

Activity2.4 μM

MethodMIC