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MYP_058216
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Basic Information
Antiviral lectin scytovirin
Antimicrobial
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
95 amino acids
C392H600N132O140S10
Standard
Sequence
GSGPTYCWNEANNPGGPNRCSNNKQCDGARTCSSSGFCQGTSRKPDPGPKGPTYCWDEAKNPGGPNRCSNSKQCDGARTCSSSGFCQGTAGHAAA
Physicochemical Analysis
9722.41 Da
8.59
3.75
3.34
0.0395
-1.10
0.42
-0.19
30.60
8.42
0.0632
13980.00
14605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4387.81
-76.02
158.0
155.0
305.0
674.0
18.0
107.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081341 VERIFIED: YES
Provenance & Taxonomy
Scytonema varium [other]
Bombinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID12614152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12614152/
RECORD: Rec_0108463 VERIFIED: YES
Provenance & Taxonomy
Scytonema varium [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-55; 20-32; 26-38; 68-80; 74-86
Bio-Activity Profile
Antimicrobial Antiviral Host defense
PaperPDB 2QSK structural record; X-ray; 1.00 A; chain A; residues 1-95
RECORD: Rec_0200279 VERIFIED: YES
Provenance & Taxonomy
Scytonema varium [Bacterium]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 12614152 | PubMed PMID: 16647158 | PubMed PMID: 17965185 PMID12614152;16647158;17965185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12614152/
RECORD: Rec_0332261 VERIFIED: YES
Provenance & Taxonomy
Scytonema varium [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
The five disulfide bonds are proposed as Cys7-Cys55, Cys20-Cys32, Cys26-Cys38, Cys68-Cys80, and Cys74-Cys86 (Moulaei T et al Protein Sci 2012)
Bio-Activity Profile
Antiviral
PaperA potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.
RECORD: Rec_0333947 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23173204 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23173204/