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MYP_058205
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Basic Information
PMAP-36 (2-17) [T9W]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C104H186N40O17
Standard
Sequence
RFRRLRKKWRKRLKKI
Physicochemical Analysis
2268.85 Da
12.00
10.76
10.54
0.6722
-2.03
0.72
-1.07
66.97
73.12
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1017.11
-6.00
41.0
28.0
85.0
161.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027395 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 12228
128 μM
MBC
PMID25494332;25753629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0032497 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 21625[LC = 9+-1.8 microg/ml]
PMID25494332;25753629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0034315 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
macrophage cells is larger than 256 μM
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0035242 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa LCCI
2 μM
MIC
PMID25494332;25753629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0057371 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
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