Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC426H646N122O123S12

DescriptionStandard

        MEAFGVASAVDLACMFILESTAVPFSEVWRKNEEVGSIDSPVGEHQQPGESMRPPEHFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9829.21 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.22

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0140

GRAVY Index-0.23

Hydrophobic Moment 0.57

Boman Index0.00

Instability Index70.59

Aliphatic Index 52.64

Aromaticity 0.1034

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3895.46

LogP -40.20

H-bond Donors 142.0

H-bond Acceptors 138.0

Rotatable Bonds 318.0

Heavy Atoms 683.0

Ring Count 20.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221299 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus kisutch [Animal]

FamilyHepcidin

Tax ID8019

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal