‹ ›
MYP_058165
← PREVIOUS NEXT → BACK
Basic Information
RGD-La
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C90H154N26O22
Standard
Sequence
RGDLLRHVVKILEKYL
Physicochemical Analysis
1952.35 Da
9.70
1.85
1.59
0.1155
-0.04
0.82
-0.10
33.08
158.12
0.0625
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
799.17
-3.12
29.0
25.0
68.0
138.0
2.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0114616 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
A-549
50 μg/mL
Inhibition
PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0117166 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD-modified temporin analogs
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
SW-1116 (colorectal cancer)
50 μg/mL
MTT/MTS assay
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0133884 VERIFIED: YES
Provenance & Taxonomy
Arg-Gly-Asp [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HL-7702(L-02) (36.25 Inhibition ratio at 50 μg/ml)
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0154220 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD-modified temporin analogs
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HEK-293T (renal cancer)
50 μg/mL
MTT/MTS assay
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0181488 VERIFIED: YES
Provenance & Taxonomy
Arg-Gly-Asp [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
(72.69 Inhibition ratio at 50 μg/ml)
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
FIRST PREV 1 2 3 4 ... 6 NEXT LAST
Showing 5 records on this page · Page 2 of 6