Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length489 amino acids

Chemical FormulaC2427H3869N619O696S17

DescriptionStandard

        MFLWCVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALALVPDTGVILSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVTSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIADINPHLKTLNVLAKVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTNMLYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGGFIPQIEKMYPGLMMKLLVETVKEPLMTFEPNNMTVQASSTVTAYAIQPNSTLSPLFVLNLEGSVSTHIYVTELKLAGNVTLNKIDMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLQVLKVSLYIYHFALFQCSTVQVIHSHYQVKITV
    

Molecular Weight53400.51 Da

Isoelectric Point (pI)9.14

Net Charge (pH 7.0)9.17

Net Charge (pH 7.4) 8.38

Charge Density (pH 7.0) 0.0187

GRAVY Index0.23

Hydrophobic Moment 0.72

Boman Index0.18

Instability Index30.57

Aliphatic Index 106.38

Aromaticity 0.0859

Extinction Coeff. Reduced 44810.00

Extinction Coeff. Oxidized 45060.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285422 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria