Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length527 amino acids

Chemical FormulaC2515H3910N690O790S21

DescriptionStandard

        MGRRVITHGRGQALDGDKTTTGAKCISSLPNVKNCGKGVVRLGDRTTVCPKCSKPGTIITGELSVFYGGSPAAVDGSFVMCGCPMGTNRVIAPIGQVSISEELSQSHANNDFLPQQPPPPMPVFAKSCLRGMGCTDAGTSPEPSQNFMPVGYFMATPFSGDDQYNTQHIADNTSLNNSLAESEQHVETAATFPVGAVVFSWISGQFSTVGTWGAKSAASNIGEILVGGAGAPVAAFLVAMMPGKLNSGEQDFIDKMRLSQIADIEGTAPTRVRFAWEEQADGHMMPTGYHTDANGGWDQVPVRNMVLNSQTGNYEFTTEGIKPITIYWNPAKLDFEFKNNTGNQEPLNLPPTITVTPIPEETGGYIETYPADEKNFSDYILILPIPDIPPIYIYFSKPDVNFLEVDLYENFKGRSRQQKYQVDHIPSAAAVKANLKENNPDLTTSELNEKVGRVASIAVPRNTHLYDSETYGGRNNEGQIAKDLRAAADSNFNAIIPSLKNEGATSEQIENARKRIHKLNEEQGLYK
    

Molecular Weight57125.46 Da

Isoelectric Point (pI)5.22

Net Charge (pH 7.0)-13.72

Net Charge (pH 7.4) -14.64

Charge Density (pH 7.0) -0.0260

GRAVY Index-0.39

Hydrophobic Moment 0.75

Boman Index0.03

Instability Index39.46

Aliphatic Index 71.46

Aromaticity 0.0797

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51840.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370725 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli