Peptide Database

Peptide NameEsculentin-2JDa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H295N45O48S3

DescriptionStandard

        GLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC
    

Molecular Weight3821.62 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1011

GRAVY Index0.36

Hydrophobic Moment 0.64

Boman Index0.17

Instability Index-1.55

Aliphatic Index 105.68

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1508.74

LogP -13.84

H-bond Donors 54.0

H-bond Acceptors 55.0

Rotatable Bonds 136.0

Heavy Atoms 265.0

Ring Count 1.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417460 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana andersonii [Animal]

FamilyEsculentin

Structure & Mods

ConfigLinear peptide with a single intramolecular disulfide-stabilized loop [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Disulfide31-37

Bio-Activity Profile

Function

Antimicrobial Antifungal

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