Peptide Database

Peptide NamePyosin cloacin_T_dom domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC348H519N93O107S3

DescriptionStandard

        MTVQGYHVSPESGLDNVLVRMMRLNPTTGNYEFWEPGENRPTILWTPNEQEFKAPPHTGNEEQPFIPS
    

Molecular Weight7813.60 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-5.30

Net Charge (pH 7.4) -5.64

Charge Density (pH 7.0) -0.0780

GRAVY Index-0.84

Hydrophobic Moment 0.66

Boman Index-0.03

Instability Index46.16

Aliphatic Index 52.94

Aromaticity 0.1029

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3180.61

LogP -31.60

H-bond Donors 103.0

H-bond Acceptors 107.0

Rotatable Bonds 241.0

Heavy Atoms 551.0

Ring Count 20.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238174 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus laumondii subsp. clarkei [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperWhole-genome-based revisit of Photorhabdus phylogeny: proposal for the elevation of most Photorhabdus subspecies to the species level and description of one novel species Photorhabdus bodei sp. nov., and one novel subspecies Photorhabdus laumondii subsp. clarkei subsp. nov. PMID29877789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29877789/