Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC922H1467N255O248S7

DescriptionStandard

        PTTPPMAHEPTLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQELYPDQPMELHLWARQQPLLSCHPDALHGTLLGSAEAFVVLPNATRVPAFLLNIDANVTGRPTISRNRLGGTVRLTGLVPTLSWGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRAVP
    

Molecular Weight20316.53 Da

Isoelectric Point (pI)10.04

Net Charge (pH 7.0)7.30

Net Charge (pH 7.4) 6.97

Charge Density (pH 7.0) 0.0396

GRAVY Index0.05

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index57.37

Aliphatic Index 97.01

Aromaticity 0.0761

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7900.16

LogP -90.31

H-bond Donors 274.0

H-bond Acceptors 266.0

Rotatable Bonds 637.0

Heavy Atoms 1432.0

Ring Count 41.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111188 VERIFIED: NO

Provenance & Taxonomy

OrganismEmberiza fucata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria