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MYP_058081
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Basic Information
DefMT5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
37 amino acids
C190H297N61O46S7
Standard
Sequence
GFFCPYNGYCDRCRKKLRRRGGYCGGRWKLTCICIMN
Physicochemical Analysis
4396.23 Da
9.69
7.70
7.40
0.2080
-0.53
0.69
-0.22
60.89
42.16
0.1622
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1771.78
-16.71
72.0
61.0
144.0
304.0
8.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094316 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
L. seeligeri
15 μM
MIC
PaperIxodes ricinus defensins attack distantly-related pathogens.
RECORD: Rec_0104492 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Fusarium graminearum
4 μM
IC50
PaperIxodes ricinus defensins attack distantly-related pathogens.
RECORD: Rec_0157369 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Gram- Pseudomonas aeruginosa
15 μM
MIC
PaperIxodes ricinus defensins attack distantly-related pathogens.
RECORD: Rec_0158463 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
L. grayi
8 μM
MIC
PaperIxodes ricinus defensins attack distantly-related pathogens.
RECORD: Rec_0166677 VERIFIED: YES
Provenance & Taxonomy
Androctonus australis [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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