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MYP_058059
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Basic Information
Oxyntomodulin
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C192H295N59O60S
Standard
Sequence
HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA
Physicochemical Analysis
4421.82 Da
9.82
2.85
2.58
0.0769
-1.22
0.66
-0.30
76.50
44.86
0.1351
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2014.75
-24.85
71.0
65.0
149.0
312.0
7.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275227 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Oxyntomodulin
9940
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation
Experimental: 1.7 hours; /6120 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PMID19602537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19602537/
RECORD: Rec_0287997 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]; Sus scrofa [Animal]
Oxyntomodulin
32630;9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
GLP-1 receptor agonist Glucagon receptor agonist
Radioimmunoassay
Human plasma (Dose i/v injected), in vivo; 720 s
PMID3147901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3147901/
RECORD: Rec_0296271 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 56.8%, E 0.0%, T 10.8%, C 32.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0329828 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Oxyntomodulin
9615
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation
Experimental: 1.7 hours; /6120 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PMID19602537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19602537/
RECORD: Rec_0338698 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
Glucagon
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/GLUC_CANFA/entry
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