Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC364H580N98O97S9

DescriptionStandard

        MAMTQLLLLLVALLVLGHVPPGRSEFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKNGYE
    

Molecular Weight8169.68 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0496

GRAVY Index0.03

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index68.60

Aliphatic Index 86.85

Aromaticity 0.0822

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3065.91

LogP -24.38

H-bond Donors 111.0

H-bond Acceptors 112.0

Rotatable Bonds 258.0

Heavy Atoms 568.0

Ring Count 16.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079432 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic