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MYP_058049
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Basic Information
Met-enkephalin-Arg-Gly-Leu
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
8 amino acids
C41H61N11O10S
Standard
Sequence
YGGFMRGL
Physicochemical Analysis
900.06 Da
8.75
0.76
0.55
0.0949
0.19
0.55
0.26
-6.47
48.75
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
349.15
-2.06
13.0
12.0
28.0
63.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145051 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
RECORD: Rec_0208353 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Opioid
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0220038 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 37.5%, C 62.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0221293 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Met-enkephalin-Arg-Gly-Leu
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
RECORD: Rec_0255271 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperMcDonald J., Lambert D. G.. Opioid mechanisms and opioid drugs. Anaesthesia and Intensive Care Medicine, 2007, 9:1, 33-37.
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