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MYP_058041
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Basic Information
Tric-COOH
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGLXGGLXGIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051904 VERIFIED: YES
Provenance & Taxonomy
Ascomycetes [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
Methyl ester
X=Aib
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/
RECORD: Rec_0120313 VERIFIED: YES
Provenance & Taxonomy
Ascomycetes [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X=Aib
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0194526 VERIFIED: YES
Provenance & Taxonomy
Ascomycetes [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
Methyl ester
X=Aib
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/
RECORD: Rec_0207448 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octanoylation
Methyl ester
Aib (α-aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial
Human erythrocytes
15 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19399781/ PMID19399781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19399781/
RECORD: Rec_0275250 VERIFIED: YES
Provenance & Taxonomy
Ascomycetes [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X=Aib
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
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