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MYP_058024
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Basic Information
CEME
Anticancer
Anticancer ▸ Anti-proliferative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
26 amino acids
C136H232N32O30
Standard
Sequence
KWKLFKKIGIGAVLKVLTTGLPALIS
Physicochemical Analysis
2795.49 Da
10.60
4.76
4.54
0.1829
0.84
0.49
0.33
-4.21
150.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
988.61
-3.00
35.0
35.0
95.0
198.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0313658 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa OT97
0.7 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0329693 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa PAO1 and mutants
2 μg/mL
MIC
PaperSalt-resistant alpha-helical cationic antimicrobial peptides.
RECORD: Rec_0330978 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium vaccae strain (ATCC 15483)
0.3 μM
IC50
PMID23716047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23716047/
RECORD: Rec_0332690 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Cowan 1
1 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0348775 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
including resistance strains Acinetobacter baumannii
2-8 μg/mL
MIC
PaperSalt-resistant alpha-helical cationic antimicrobial peptides.
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