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MYP_058024
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Basic Information
CEME
Anticancer
Anticancer ▸ Anti-proliferative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
26 amino acids
C136H232N32O30
Standard
Sequence
KWKLFKKIGIGAVLKVLTTGLPALIS
Physicochemical Analysis
2795.49 Da
10.60
4.76
4.54
0.1829
0.84
0.49
0.33
-4.21
150.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
988.61
-3.00
35.0
35.0
95.0
198.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086334 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis Bs11
0.4 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0092633 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial Antileishmanial Antibiotic
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0099500 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
D-[CA--M-NH2]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibiotic Antiparasitic Antimalarial
Plasmodium falciparum F32 Tanzania
Percent inhibition; Microscopy (Acridine orange staining)
PaperAll-D amino acid-containing channel-forming antibiotic peptides PMID1693777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1693777/
RECORD: Rec_0156269 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes
2 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0163236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D21
0.3 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
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