Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC418H653N113O124S13

DescriptionStandard

        MKTFSVAVAVAVVLTFICFQQSSAVPVTEQEQELEEPMSMDYPAAAHEEASVDSWKMLYNSRHKRGIKCRFCCGCCTPGICGVCCRF
    

Molecular Weight9662.18 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0161

GRAVY Index0.14

Hydrophobic Moment 0.45

Boman Index0.08

Instability Index68.24

Aliphatic Index 66.09

Aromaticity 0.0920

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3769.73

LogP -37.89

H-bond Donors 139.0

H-bond Acceptors 138.0

Rotatable Bonds 313.0

Heavy Atoms 668.0

Ring Count 15.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049410 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0147816 VERIFIED: NO