Peptide Database

Peptide NameIota-conotoxin RXIA

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC212H318N54O66S8

DescriptionStandard

        GPSFCKADEKPCEYHADCCNCCLSGICAPSTNWILPGCSTSSFFKI
    

Molecular Weight4935.64 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.61

Charge Density (pH 7.0) -0.0267

GRAVY Index0.07

Hydrophobic Moment 0.41

Boman Index0.13

Instability Index21.70

Aliphatic Index 48.91

Aromaticity 0.1087

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1877.64

LogP -22.24

H-bond Donors 71.0

H-bond Acceptors 74.0

Rotatable Bonds 151.0

Heavy Atoms 340.0

Ring Count 11.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120442 VERIFIED: YES

Provenance & Taxonomy

OrganismConus radiatus [Animal]

Familyconotoxin I1 superfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide5-19; 12-22; 18-27; 21-38

Other Mods2-Pro: 4-hydroxyproline; partial; 11-Pro: 4-hydroxyproline; partial; 29-Pro: 4-hydroxyproline; 44-Phe: D-phenylalanine

Bio-Activity Profile

Function

Toxin Venom conotoxin I1 superfamily Pathogenesis-associated Conotoxin

RECORD: Rec_0306732 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Miscellaneous