Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC376H605N109O97S8

DescriptionStandard

        MRIPVLLFIIFFFMSQVLPARGKFKEICERPNGSCRDFCLKTEIHVGRCLNSRHCCLPLGHQPRIESTTPKKD
    

Molecular Weight8461.02 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.0783

GRAVY Index-0.12

Hydrophobic Moment 0.47

Boman Index-0.04

Instability Index56.98

Aliphatic Index 82.74

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3292.99

LogP -27.82

H-bond Donors 120.0

H-bond Acceptors 114.0

Rotatable Bonds 279.0

Heavy Atoms 590.0

Ring Count 15.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145842 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence