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MYP_057853
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Basic Information
SrnA2
Antimicrobial
Standard
32 amino acids
C155H232N44O45S3
Standard
Sequence
GWFTAVQLTLAGRCGRWFTGSYECTTNNVKCG
Physicochemical Analysis
3527.96 Da
8.68
1.73
1.48
0.0541
-0.11
0.60
0.09
44.76
48.75
0.1562
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1455.00
-16.87
56.0
50.0
110.0
247.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021198 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. pneumoniae V4122578 or W81002644
0.5-1 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0043636 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
P. gingivalis ATCC 33277
32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0158263 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
N. gonorrhoeae V3091967
64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0174002 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S-mutans UA159
>64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0220767 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. agalactiae W73106655 or W70407881
16-32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
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