Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC271H434N70O86S6

DescriptionStandard

        MSKFDDFDLDVVKVSKQDSKITPQWKSESVCTPGCVTGVLQTCFLQTITCNCHISK
    

Molecular Weight6241.15 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.81

Charge Density (pH 7.0) -0.0082

GRAVY Index-0.11

Hydrophobic Moment 0.47

Boman Index0.02

Instability Index64.84

Aliphatic Index 72.86

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2528.84

LogP -28.44

H-bond Donors 91.0

H-bond Acceptors 93.0

Rotatable Bonds 208.0

Heavy Atoms 433.0

Ring Count 8.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209945 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence