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MYP_057837
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Basic Information
NS5A-derived peptide C5A [I10S]
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Anti-HIV ▸ HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C106H149N25O30S
Standard
Sequence
SWLRDIWDWSCEVLSDFK
Physicochemical Analysis
2285.53 Da
4.23
-2.54
-2.77
-0.1414
-0.33
0.62
0.03
32.57
81.11
0.2222
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
903.20
-4.56
34.0
29.0
71.0
162.0
7.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099935 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV)
PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/
RECORD: Rec_0114126 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV
PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/
RECORD: Rec_0134340 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0207028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
28 μM
Hemolysis
PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/
RECORD: Rec_0246043 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Hemolytic
Human erythrocytes
28
MHC
PaperRational design of peptides with anti-HCV/HIV activities and enhanced specificity. Chem Biol Drug Des. 2011 Nov;78(5):835-843. doi: 10.1111/j.1747-0285.2011.01201.x. PMID: 21801309. PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/
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