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MYP_057825
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Basic Information
Chromogranin A (31-76)[D15H], CGA-N46
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
46 amino acids
C232H383N73O69S2
Standard
Sequence
PMPVSQECFETLRGHERILSILRHQNLLKELQDLALQGAKERAHQQ
Physicochemical Analysis
5363.10 Da
7.38
0.22
-0.01
0.0049
-0.67
0.76
-0.17
75.91
97.61
0.0217
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2321.84
-22.65
80.0
74.0
187.0
376.0
6.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida krusei ATCC 6258
370 μM
MIC
PMID27165480 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27165480/
RECORD: Rec_0054942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
740 μM
Hemolysis
PMID27165480 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27165480/
RECORD: Rec_0176364 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0268032 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 2048
500 μM
MIC
PMID27165480 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27165480/
RECORD: Rec_0281952 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal Anticancer
Candida albicans, C. glabrata, C. parapsilosis, C. krusei
PaperOptimization of the expression conditions of CGA-N46 in Bacillus subtilis DB1342(p-3N46) by response surface methodology
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