Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC431H678N122O124S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQEPEEAGSNDTPVVAHQEMSMESWMMPNHIRQKRQSHLSLCRWCCNCCRGNKGCGFCCKF
    

Molecular Weight10001.65 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.09

Instability Index67.93

Aliphatic Index 69.33

Aromaticity 0.0778

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3915.71

LogP -40.56

H-bond Donors 143.0

H-bond Acceptors 142.0

Rotatable Bonds 327.0

Heavy Atoms 691.0

Ring Count 16.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367827 VERIFIED: NO

Provenance & Taxonomy

OrganismChelon ramada [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal