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MYP_057785
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Basic Information
PG-1 analog 10
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
18 amino acids
C89H149N33O22S2
Standard
Sequence
RGGRLCYTRPRFTVCVGR
Physicochemical Analysis
2097.47 Da
11.42
4.74
4.51
0.2633
-0.44
0.53
-0.33
4.47
53.89
0.1111
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
919.42
-10.47
38.0
29.0
66.0
146.0
3.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006843 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
6-15
APD analysis reveals that this sequence is unique and shows only very low similarity (83.33%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
penicillin-resistant Staphylococcus aureus 1206
12.5 μg/mL
MIC
PaperDesign of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues.
RECORD: Rec_0068873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1206
12.5 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
RECORD: Rec_0069660 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis BR151
3.1 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
RECORD: Rec_0093124 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
6-15
APD analysis reveals that this sequence is unique and shows only very low similarity (83.33%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
vancomycin-resistant E. faecium A634
3.1 μg/mL
MIC
PaperDesign of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues.
RECORD: Rec_0116686 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1206
25 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
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