Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC560H900N150O164S4

DescriptionStandard

        PDLNGHEKYGLGNVKYNISRIRVTAVEFPSASISLLPGTGIKLVIANASLTIDMNWSLRTWMFKDTGRSTVYISKVFVTAIFSMPLDHTGHTLISLISCRTTSGDIDIKLNGKS
    

Molecular Weight12486.30 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.10

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index13.29

Aliphatic Index 100.88

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5023.67

LogP -50.95

H-bond Donors 181.0

H-bond Acceptors 175.0

Rotatable Bonds 413.0

Heavy Atoms 878.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0176213 VERIFIED: NO

Provenance & Taxonomy

OrganismNothocercus julius [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria