Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC928H1406N208O281S8

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPYIDLDLKGIVYPAGNYTGSPYVAAPFAIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTATEIPLISLQQDSFTLEMQGSMEVFAVLPDSTTQLLFTMNVAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20228.83 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.52

Charge Density (pH 7.0) -0.0723

GRAVY Index0.31

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index42.23

Aliphatic Index 96.01

Aromaticity 0.1366

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7735.88

LogP -80.91

H-bond Donors 263.0

H-bond Acceptors 276.0

Rotatable Bonds 641.0

Heavy Atoms 1425.0

Ring Count 36.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166372 VERIFIED: NO

Provenance & Taxonomy

OrganismChauna torquata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria