Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length185 amino acids

Chemical FormulaC869H1392N262O260S16

DescriptionStandard

        MKGKTAAGGGAICAIAVMITIVMGNGNVRTNLAGLELIGNAEGCRRDPYMCPAGVWTDGIGNTHGVTPGVRKTDQQIAADWEKNILIAERCINQHFRGKDMPDNAFSAMTSAAFNMGCNSLRTYYSKARGMRVETSIHKWAQKGEWVNMCNHLPDFVNSNGVPLPGLKIRREEERQLCLTGLVNE
    

Molecular Weight20182.99 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.81

Net Charge (pH 7.4) 3.25

Charge Density (pH 7.0) 0.0206

GRAVY Index-0.28

Hydrophobic Moment 0.73

Boman Index0.01

Instability Index23.37

Aliphatic Index 74.92

Aromaticity 0.0595

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8411.55

LogP -99.87

H-bond Donors 296.0

H-bond Acceptors 284.0

Rotatable Bonds 673.0

Heavy Atoms 1407.0

Ring Count 26.0

Amide Bonds 204.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0126439 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence